Home

The Baldwin Lab is a part of the UNC Lineberger Comprehensive Cancer Center, an NCI designated Cancer Center associated with the UNC School of Medicine and the University of North Carolina at Chapel Hill. Our laboratory focuses on the regulation and biological functions of the transcription factor NF-kappaB and on the role of NF-kappaB in disease, with a particular emphasis on cancer and cancer therapy. These studies focus on the signaling pathways which target NF-kappaB, on the biological mechanisms which NF-kappaB controls, and on the ability of NF-kappaB to promote basic oncogenic mechanisms as well as resistance to cancer therapy.